Introduction

Isolution is a non-commercial software written by the Object Pascal programming language, designed to provide a simple and reliable solution for the solution-based isotope data reduction. The software is able to visualize and process the isotopic data that are generated from a suite of isotopic fractionation correction models:

1. Internal normalization model.
2. Standard sample bracketing (SSB) model.
3. Inter-element normalization model.
4. Double-spike correction model.

Moreover, the optimization and calibration of double-spike are prerequisites for the use of double-spike technique. Thus, this software is accomplished with other two significant features.

5. Double-spike calibration function.
6. Double-spike optimization function.

In addition, a series of functions are integrated to meet various task requirements and simplify operations.

7. Built-in isobaric interferences correction function.¹
8. Customized correction function.
9. Automatic identification of sample type (sample/standard/blank) to establish SSB correction information.
10. Blank identification and correction.